James Haines married Nancy Williams Smith in Fayette County on November 12, 1840. They raised 6 children, the first in Allen County, Ohio and the rest in Grant County, Indiana: Savanah (b 1844), Rebecca (b 1846), Melton (b 1848), James (b 1850), Samuel (b 1852), Alfred (b 1855), and Constantine (b 1858). Where nor when James died is not known, but possibly in Indiana.